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- W2376133085 abstract "Objective To study the expression and clinical significance of P-gp in colorectal carcinoma.Methods Immunohistochemistry was used to examine the P-gp expression in 78 cases of colorectal carcinoma and 31 cases of normal tissues.Results The positive expression of P-gp in colorectal carcinoma was 83.3%(65/78),higher than that in normal tissue(P0.05).The expression of P-gp was related to the degree of invasion(P0.05),but not related to sex,age,clinical staging and nodal metastasis(P0.05).Conclusion P-gp play important roles in the primary multidrug resistance of colorectal carcinoma.Detecting the expression of P-gp in colorectal carcinoma has the referential significance with regard to the choice of drugs and plan in colorectal carcinoma chemotherapy." @default.
- W2376133085 created "2016-06-24" @default.
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- W2376133085 date "2009-01-01" @default.
- W2376133085 modified "2023-09-23" @default.
- W2376133085 title "Expression and significance of P-gp in colorectal carcinioma" @default.
- W2376133085 hasPublicationYear "2009" @default.
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