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- W2376137717 abstract "The existence of blood-brain barrier(BBB) makes it impossible for 98% medicines to enter the brain.This is an important restrictive factor for the development of central nervous drugs.By nanoparticle delivery system,drugs can cross the BBB and increase the drug concentration in brain.This system is a better carrier for drugs to target brain,but the mechanism how it permeate the BBB is not completely understood.Since Kreuter proposed six plausible mechanisms for nanoparticles(NP) across the BBB in 2001,it has become a hot spot to investigate these mechanisms in order to enhance the drug-loaded NP permeability across the BBB.This article mainly reviewed the present research progress in mechanisms of NP across the BBB." @default.
- W2376137717 created "2016-06-24" @default.
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- W2376137717 date "2008-01-01" @default.
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- W2376137717 title "Progress in mechanisms of nanoparticles across the blood-brain barrier" @default.
- W2376137717 hasPublicationYear "2008" @default.
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