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- W237614074 abstract "Objective:To determine the predictors of acute renal failure (ARF) that occur in major burns. Methods:The data of 75 patients with moderate to severe thermal burn injury-second to third degree with 20% -70% of total body surface area (TBSA) in our hospital were analyzed. All patients were subjected to routine investigations including: Serum creatinine(Scr), blood urea nitrogen(BUN), fractional excretion of sodium (FeNa) and microalbuminuria (mALB) on day 0, 3, 7, 14 and 21 of hospitalization. Results: 14 patients (18.7 %) developed ARF, and 10 patients of these required blood purification therapy. The size of burn and occurrence of septicemia in group with ARF were obviously higher than that in group without ARF (P all0. 05). The levels of Scr and Bun in group with ARF from day 7 and day 14 respectively were obviously higher than that in group without ARF (P all0. 05). The group with ARF showed an increase level of mALB that reached 3-4 folds above its normal level on day 0 and reached the maximum on day 21, and it was obviously higher than that in group without ARF in the period of observation (P all0. 05). FeNa was above 2% in all cases with ARF. Burn size and occurrence of septicemia were the only risk factor of ARF using multiple regression analysis (R 0.52 and 0.23 respectively, P all0. 05). Conclusions: In this study, ARF is related to the size of burn and occurrence of septicemia. mALB is a useful early indicator for prediction of renal outcome." @default.
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- W237614074 date "2009-01-01" @default.
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- W237614074 title "Early indicators of acute renal failure in burned patients" @default.
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