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- W2376162433 abstract "Objective The changes of VGluT1-like immunoreactivity(VGluT1-LI) in the trigeminal complex of the rat in different survival time after unilateral mandibular nerve transection were examined. Methods Immunocytochemical staining method and image analysis technique were performed. Results Many VGluT1-LI were observed in the trigeminal complex of the normal rat and were mainly distributed in the terminals.A weak decrease of VGIuT1-LI in the dorsal part of principal trigeminal nucleus(Vp) could be detected at the first week after unilateral transection of mandibular nerve(P0.05).From two weeks after the transection,a sharp decrease of VGIuTI-IR was shown not only in the dorsal part of caudal spinal trigeminal nucleus(Vc) and interpolar spinal trigeminal nucleus(Vi),but also in the supratrigeminal nucleus(Vsup) and the motor trigeminal nucleus(Vmo) besides the dorsal part of Vp(P0.01),and the reduction of VGluTI-IR on the ipsilateral side was much more evident than those observed at the first week(P0.01).The decrease of VGluTI-IR was much significant at three weeks after transection(P0.01),and the decrease on the ipsilateral side was much more evident than those observed at the first and two weeks(P0.01). The VGluTI-IR almost disappeared in Vmo.Conclusion(1)Transection of the peripheral branches of primary afferent neurons could induce down-regulation of VGluTI-IR in their central terminals.(2)Part of VGluT1-immunoreactive terminals in trigeminal complex originated from the primary afferent neurons." @default.
- W2376162433 created "2016-06-24" @default.
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- W2376162433 date "2006-01-01" @default.
- W2376162433 modified "2023-09-26" @default.
- W2376162433 title "CHANGES OF EXPRESSION OF VESICULAR GLUTAMATE TRANSPORTER 1 IN THE RAT TRIGEMINAL COMPLEX AFTER MANDIBULAR NERVE TRANSECTION" @default.
- W2376162433 hasPublicationYear "2006" @default.
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