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- W2376191837 abstract "Objective To investigate the effects of chronic intermittent hypoxia(CIH) on blood pressure and sympathetic nerve activity in rats.Methods Male SD rats(n=40) were randomly divided into control and CIH groups.The conscious noninvasive method with tail cuff was performed in rats to record the systolic blood pressure(SBP) after exposure to 5,10,15 days of CIH.Mean arterial pressure(MAP),heart rate(HR) and renal sympathetic nerve activity(RSNA) were recorded in vivo on PowerLab data-acquisition systems,while plasma norepinephrine(NE) was measured after CIH.Results SBP,MAP and RSNA were significantly enhanced in CIH group compared to those of control group after 15 days of CIH,and the plasma NE level of rats in CIH group was significantly higher than that of the control group.Conclusions CIH can induce increased blood pressure and sympathetic overactivity in rats." @default.
- W2376191837 created "2016-06-24" @default.
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- W2376191837 date "2012-01-01" @default.
- W2376191837 modified "2023-09-23" @default.
- W2376191837 title "Effects of chronic intermittent hypoxia on blood pressure and sympathetic nerve activity in rats" @default.
- W2376191837 hasPublicationYear "2012" @default.
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