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- W2376252626 abstract "【Objective】To investigate the short-term efficacy of antiviral treatment in patients with different stages of acute-on-chronic hepatitis B liver failure.【Methods】A total of 352 patients with acute-on-chronic hepatitis B liver failure,were classified to 120 cases of early stage,149 cases of medium stage and 83 cases of later stage according toDiagnosis and treatment guideline for liver failurewere rolled.Every stage was divided into two groups,one was treated with antiviral therapy(LAM or ETV or Ltd)and routine supportive therapy,and the control group was treated with supportive therapy only.The clinical features and the short-term(24 weeks)efficacy of antiviral therapy were compared among three stages.【Results】There was significant difference in the mortality among the patients with different stages of acute-on-chronic hepatitis B liver failure(P0.05).As the liver function got worse,there was lower survival rate of patients.Otherwise,there was no significant difference in the mortality between the antiviral therapy group and the control group of the early and later stage(P0.05).Only the survival rate of patients in the antiviral therapy group was higher than that in control group of the medium stage(P0.05).【Conclusion】Early therapy can improve survival rate of patients of acute-on-chronic hepatitis B liver failure.And antiviral therapy significantly improve survival rate of patients of medium stage." @default.
- W2376252626 created "2016-06-24" @default.
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- W2376252626 date "2010-01-01" @default.
- W2376252626 modified "2023-09-24" @default.
- W2376252626 title "Short-term Efficacy of Antiviral Treatment in Patients with Different Stages of Acute-on-chronic Hepatitis B Liver Failure" @default.
- W2376252626 hasPublicationYear "2010" @default.
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