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- W2376258935 abstract "A comparison was made for the size-dependent DNA damage induced by both nano dioxide manganese particles(Nano-MnO2)and normal size dioxide manganese particles(Nor-MnO2). Hela cells were exposed to different concentrations of both Nano-MnO2 and Nor-MnO2 (0, 100, 200, 400μg·mL-1), respectively. The DNA damage of Hela cells was measured by the comet assay after 24h MnO2-cultivated. Results showed that the Tail DNA% and Tail Moment were both significantly increased after exposed to both Nano-MnO2 and Nor-MnO2 when compared with the control(p0.01 for all). At the same concentration level, Nano-MnO2 could induce more serious DNA damage than Nor-MnO2(p0.01 for all). The results suggested that Nano-MnO2 should have more serious toxic effect regarding to DNA damage of the Hela cells than that of Nor-MnO2." @default.
- W2376258935 created "2016-06-24" @default.
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- W2376258935 date "2008-01-01" @default.
- W2376258935 modified "2023-09-27" @default.
- W2376258935 title "Size-Dependent Toxicity of Dioxide Manganese Particles on DNA Damage in Hela Cells" @default.
- W2376258935 hasPublicationYear "2008" @default.
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