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- W2376263362 abstract "Objective To investigate the variance of serum Nicotinamide phosphoribosyltransferase(NAMPT)level during CPB and its relevance to glucose metabolism.Methods Thirty-six patients for elective heart valve replacement surgery were enrolled in this study.The blood samples were collected 5min after anesthesia(T1),5min after aortic clamping(T2),5min after rewarming(T3), 5min after aortic clamp releasing(T4)and 5min after the end of operation(T5).Serum levels of NAMPT,insulin and blood glucose were detected,and insulin resistance index was calculated.The correlation between serum NAMPT level and glucose metabolism was then analyzed.Results Compared with T1,serum levels of NAMPT and insulin,blood glucose and insulin resistance index were significantly elevated at T2-T5(P0.05),moreover,the levels were highest at T3.There was a positive correlation between the variance of serum insulin level and NAMPT level(r=0.873,P0.01). Conclusion The serum NAMPT level is positively correlated with serum insulin level during CPB." @default.
- W2376263362 created "2016-06-24" @default.
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- W2376263362 date "2014-01-01" @default.
- W2376263362 modified "2023-09-23" @default.
- W2376263362 title "The variance of Nicotinamide phosphoribosyltransferase(NAMPT)during CPB and its correlation with glucose metabolism" @default.
- W2376263362 hasPublicationYear "2014" @default.
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