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- W2376283736 abstract "Human peripheral blood lymphocyte subpopulations were identified by immunofluorescence withlabelled monoclonal antibodies against surface antigens (CD3/CD19, CD3/CD16/CD56 and CD4/CD8) and T, B, NK and T subsets were scored by flow cytometry on a FACScan. Blood samples were irradiated with 25-250 mGy X-rays and cultured for 72 hours in RPMI 1640 medium supplemented with fetal calf serum. It was found that the percentage of total and helper T cells as well as the helper to suppressor T ratio increased with time at the expense of B and NK cells while the suppressor T subset was kept around the normal level. The general pattern of the change with time in culture was not significantly influenced by low dose radiation within 0. 1 Gy. There was no prcferntial deletion of the suppressor T subset with the doses used in the present study. Combining previous data with similar observations on the T subsets in immune organs and peripheral blood in mice after low dose whole-body irradiation, the authors emphasized the infeasibil-ity of the attempt to explain the immunoenhancement following low dose radiation by a rise in ratio of helper to suppressor T subsets." @default.
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- W2376283736 date "1993-01-01" @default.
- W2376283736 modified "2023-09-25" @default.
- W2376283736 title "CHANGES OF HUMAN PERIPHERAL BLOOD LYMPHOCYTE SUBPOPULATIONS FOLLOWING LOW DOSE X-IRRADIATION IN VITRO" @default.
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