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- W2376297968 abstract "Objective:To evaluate the effect of microalbuminuria of combined treatment with calcium antagonist(levoamlodipine)(CCB)and the ARB(candesartan),or levoamlodipine,candesartan monotherapy in elderly patients with type 2 diabetes mellitus and hypertension.Methods:Ninety cases of consecutive patients with type 2 diabetes mellitus and hypertension were randomized to receive levoamlodipine 5mg/d(n=30),candesartan 8mg/d(n=30),or a combination of levoamlodipine 5mg/d and candesartan 8mg/d(n=30)for 3 months.After 2 weeks in monotherapy group dose was doubled to the third month end.The blood pressure as well as microalbuminuria were examed pre-and-post treatment and recorded the adverse events.Results:The treatment of three groups all significantly lowered BP(P0.01),with no significantly statistical difference among them.The combination treatment group decreased urine MAU more significantly than either monotherapy approaches(P0.05).Conclusion:The combination of levoamlodipine and candesartan resulted in significantly more decrease in microalbuminuria than monotherapy with either agent in elderly patients with type 2 diabetes mellitus and hypertension." @default.
- W2376297968 created "2016-06-24" @default.
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- W2376297968 date "2010-01-01" @default.
- W2376297968 modified "2023-09-24" @default.
- W2376297968 title "Effect of Two Kinds of Drugs Combination Therapy Amlodipine,Candesartan on Microalbuminuria in Elderly Patients with Type 2 Diabetes Mellitus and Hypertension" @default.
- W2376297968 hasPublicationYear "2010" @default.
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