Matches in SemOpenAlex for { <https://semopenalex.org/work/W2376322832> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W2376322832 abstract "Objective To evaluate the effectiveness and safety of sarpogrelate hydrochloride for patients with peripheral arterial disease(PAD).Methods The randomized controlled trials(RCTs) on PAD treated by sarpogrelate hydrochloride were identified from CBM(1978 to September 2011),CNKI(1979 to May 2011),PubMed(1950 to May 2011),EMbase(1970 to May 2011) and The Cochrane Library(Issue 3,2011).According to the criteria of the Cochrane Handbook,two reviewers independently screened the studies,extracted and cross-checked the data,and assessed the methodological quality.Then meta-analysis was conducted by using RevMan 5.0 software.Results Nine RCTs involving 522 patients and 532 limbs were included,with low methodological quality in most trials.The results of meta-analyses indicated that compared with the conventional treatment,sarpogrelate hydrochloride could reduce the area of ulcers(MD= –3.22,95%CI –3.99 to –2.45),and it could increase the ankle-brachial index(SMD=0.49,95%CI 0.07 to 0.91),blood flow of dorsalis pedis artery(MD=0.16,95%CI 0.09 to 0.23) and pain-free walking distance(MD=200.87,95%CI 3.39 to 398.36).Five trials reported the adverse effects of sarpogrelate hydrochloride,most of which were mild gastrointestinal symptoms.Conclusion Based on the review,sarpogrelate hydrochloride may have positive effect on patients with PAD.However,the evidence is not strong enough due to the general low methodological quality,so the reliable conclusion has to be drawn with more high quality studies in future." @default.
- W2376322832 created "2016-06-24" @default.
- W2376322832 creator A5065359330 @default.
- W2376322832 date "2012-01-01" @default.
- W2376322832 modified "2023-09-26" @default.
- W2376322832 title "Effectiveness and Safety of Sarpogrelate Hydrochloride for Peripheral Arterial Disease: A Systematic Review" @default.
- W2376322832 hasPublicationYear "2012" @default.
- W2376322832 type Work @default.
- W2376322832 sameAs 2376322832 @default.
- W2376322832 citedByCount "0" @default.
- W2376322832 crossrefType "journal-article" @default.
- W2376322832 hasAuthorship W2376322832A5065359330 @default.
- W2376322832 hasConcept C126322002 @default.
- W2376322832 hasConcept C168563851 @default.
- W2376322832 hasConcept C1862650 @default.
- W2376322832 hasConcept C197934379 @default.
- W2376322832 hasConcept C2776478404 @default.
- W2376322832 hasConcept C42219234 @default.
- W2376322832 hasConcept C71924100 @default.
- W2376322832 hasConcept C95190672 @default.
- W2376322832 hasConceptScore W2376322832C126322002 @default.
- W2376322832 hasConceptScore W2376322832C168563851 @default.
- W2376322832 hasConceptScore W2376322832C1862650 @default.
- W2376322832 hasConceptScore W2376322832C197934379 @default.
- W2376322832 hasConceptScore W2376322832C2776478404 @default.
- W2376322832 hasConceptScore W2376322832C42219234 @default.
- W2376322832 hasConceptScore W2376322832C71924100 @default.
- W2376322832 hasConceptScore W2376322832C95190672 @default.
- W2376322832 hasLocation W23763228321 @default.
- W2376322832 hasOpenAccess W2376322832 @default.
- W2376322832 hasPrimaryLocation W23763228321 @default.
- W2376322832 hasRelatedWork W2137331958 @default.
- W2376322832 hasRelatedWork W2353286900 @default.
- W2376322832 hasRelatedWork W2360960039 @default.
- W2376322832 hasRelatedWork W2364603067 @default.
- W2376322832 hasRelatedWork W2366034987 @default.
- W2376322832 hasRelatedWork W2375459634 @default.
- W2376322832 hasRelatedWork W2378587148 @default.
- W2376322832 hasRelatedWork W2381809843 @default.
- W2376322832 hasRelatedWork W2390744446 @default.
- W2376322832 hasRelatedWork W2393997627 @default.
- W2376322832 hasRelatedWork W2774284160 @default.
- W2376322832 hasRelatedWork W2802322663 @default.
- W2376322832 hasRelatedWork W2988762460 @default.
- W2376322832 hasRelatedWork W3014213310 @default.
- W2376322832 hasRelatedWork W3016298597 @default.
- W2376322832 hasRelatedWork W3028834735 @default.
- W2376322832 hasRelatedWork W3133675267 @default.
- W2376322832 hasRelatedWork W3152242263 @default.
- W2376322832 hasRelatedWork W3164091041 @default.
- W2376322832 hasRelatedWork W3211589945 @default.
- W2376322832 isParatext "false" @default.
- W2376322832 isRetracted "false" @default.
- W2376322832 magId "2376322832" @default.
- W2376322832 workType "article" @default.