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- W2376374480 abstract "Objective To study the hypoglycemic activity of jatrorrhizine (Jat) and compare the effects of Jat, berberine (Ber), Huanglian Decoction (HLD), and compounds-mimic prescription (Ber+Jat) on blood glucose level in mice. Methods TLC-scanning method was adopted for the determination of Ber and Jat in HLD. Ber+Jat was made artificially according to the result of the TLC-scanning. Diabetic model mice were made by ip alloxan, diabetic and normal mice were given Jat, Ber, HLD, and Ber+Jat in different dose by ig and applied in the study. Blood glucose level was analyzed by spectrophotometry with glucose-oxidase. Results Jat, Ber, HLD, and Ber+Jat decreased blood glucose level of diabetic and normal mice at different degrees. HLD showed the most significant hypoglycemic activity. Jat also possessed the function of decreasing blood glucose, which was less than that of Ber at the same dose. There was no significant difference between Ber+Jat and Ber. Conclusion It implies that there are some other hypoglycemic ingredients in HLD besides Ber and Jat. Jat has no evident synergistic or antagonistic action when coexisted with Ber in natural ratio." @default.
- W2376374480 created "2016-06-24" @default.
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- W2376374480 date "2005-01-01" @default.
- W2376374480 modified "2023-09-25" @default.
- W2376374480 title "Effect of jatrorrhizine, berberine, Huanglian Decoction and compound-mimic prescription on blood glucose in mice" @default.
- W2376374480 hasPublicationYear "2005" @default.
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