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- W2376374805 abstract "Objective:To understand the changes of different serotypes of pathogenic bacteria causing the shigellosis and the distribution of virulence gene.Methods:1413 Shigella germ strains isolated from diarrhea patients were examined serotype by serum agglutination.221 strains were detected for ipaH,set1 and sen virulence gene by realtime PCR.Results:741 strains(52.4%) belonged to Shigella Sonnei,664 strains(47%) were Shigella flexneria and other 8 strains(1.2 %) respectively were Shigella dysenteriae and Shigella boydii.All the Shigella flexneria strains were composed of 19 serotypes,mainly including Shigella flexneria type 2a,4c and 1a.There is obvious difference in the distribution of the serotypes in different ages.Shigella Sonnei strains firstly became the dominant group over Shigella flexneria from 2007 and were getting prevalent the last years,reaching 79.3% in 2010.The propitiation of Shigella flexneria type 2a was increasing instead of those of 4c,with the alternate appearance of other serotypes.The distribution of ipaH,set1 and sen virulence gene among 221 strains were 95.4%,82.3% and 57.5%,respectively.The positive rate of set1 and sen virulence gene in Shigella Sonnei strains are obviously higher than those in Shigella flexneria strains.Conclusion:The distinct changes in the group and serotype of the pathogen causing shigellosis revealed that Shigella Sonnei was becoming the dominant group in Beijing.The distribution of the three virulence gene in different serotypes had difference." @default.
- W2376374805 created "2016-06-24" @default.
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- W2376374805 date "2011-01-01" @default.
- W2376374805 modified "2023-09-23" @default.
- W2376374805 title "Distribution of different serotypes and analysis of virulence genes in Shigella species in Beijing from 2004 to 2010" @default.
- W2376374805 hasPublicationYear "2011" @default.
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