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- W2376440167 abstract "MBD4/MED1 protein is one member of the MBD nucleoprotein family.It contains one MBD domain which specifically binds to methylated CpG site and one DNA glycosylase domain which has glycosidic enzyme activity.MBD4 protein can specifically bind to methylated CpG island,and is involved in DNA mismatch repair,transcription inhibition,mediator of apoptosis and associates with microsatellite instability.As an important DNA mismatch repair protein,MBD4 has been reported to play a critical role in cellular senescence.In this paper,the structure and function of MBD4 will be summarized." @default.
- W2376440167 created "2016-06-24" @default.
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- W2376440167 date "2011-01-01" @default.
- W2376440167 modified "2023-09-26" @default.
- W2376440167 title "Research progress of the structure and function of methylated CpG-binding protein MBD4/MED1" @default.
- W2376440167 hasPublicationYear "2011" @default.
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