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- W2376440568 abstract "Objective To observe the clinical effects of infliximab therapy in children with Crohn's disease. Method The hospital treated 74 cases of children with Crohn's disease in accordance with the order of admission were divided into observation group and control group, 37 cases in each group. Control group were treated with corticosteroid hormone therapy, and observation group were taken infliximab therapy. Compared two groups of clinical curative effects, endoscopic improvement after treatment, the levels of serum interleukin(IL)-2, IL-6, IL-8 before and after the treatment and adverse reactions. Result The observation group with the effective rate of treatment was 89.19%(33/37), higher than control group [83.78%(31/37)], the observation group with endoscopic improvement rate was 91.89%(34/37), better than control group [86.48%(32/37)], but there were no significant differences(P 0.05). Two groups of children with inflammatory factor levels had no significant differences before treatment(P 0.05), the two groups compared with before treatment, the levels of inflammatory factors after treatment were improved, the improvement effect of observation group was significantly better than control group, the difference was significant(P 0.05). The incidence rate of adverse reactions in the control group was 10.81%(4/37), higher than observation group [2.70%(1/37)], but the difference had no significant(P 0.05). Conclusion Children with Crohn's disease taking infliximab treatment, can effectively adjust the level of inflammatory factors, worthy of clinical popularization and application." @default.
- W2376440568 created "2016-06-24" @default.
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- W2376440568 date "2015-01-01" @default.
- W2376440568 modified "2023-09-28" @default.
- W2376440568 title "The clinical effects of infliximab therapy in children with Crohn's disease" @default.
- W2376440568 hasPublicationYear "2015" @default.
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