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- W2376454966 abstract "Two ribosome- inactivating proteins(RIP's) , α- and β - momorcharin(α - and β - MMC) have been isolated from the seeds of bitter melon ( Momordica charantia ), a traditional Chinese folk medicine. This was done by acetone fractionation and chromatographies on CM - Sephadex C - 50 and Sephadex G - 75. The molecular weights of the purified proteins as determined by ESI - MS and MALDI -TOF-MS were 28625(α - MMC),29076(β - MMC)and 28795(α - MMC),29074(β - MMC), respectively. Both of them were found to be glycoproteins and have pI values of 9.10(α - MMC) and 9. 32 (β - MMC) . Biological activity assay revealed both of them were RNAN - glycosidase and depurinate 28S rRNA in the ribosomes in a manner identical to that of trichosanthin. Here the isolation, physicochemical properties and N - terminal amino acid sequence of β- MMC are described." @default.
- W2376454966 created "2016-06-24" @default.
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- W2376454966 date "1998-01-01" @default.
- W2376454966 modified "2023-09-28" @default.
- W2376454966 title "Isolation and Characterization of α, β- Momorcharins" @default.
- W2376454966 hasPublicationYear "1998" @default.
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