Matches in SemOpenAlex for { <https://semopenalex.org/work/W2376457453> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2376457453 endingPage "40" @default.
- W2376457453 startingPage "737" @default.
- W2376457453 abstract "To investigate serum concentration of tumor necrosis factor (TNF)-alpha and its correlation with insulin resistance in pregnant women with gestational diabetes mellitus (GDM).Enzyme-linked immunosorbent assay was used to measure the fasting serum TNF-alpha levels of 42 women with GDM (28 approximately 39 gestational weeks), and 40 cases of normal pregnant women in the third trimester. Fasting plasma glucose, insulin, C-peptide and glycosylated hemoglobin (HbA1c) were also measured at the same time. Insulin sensitive index (ISI) was calculated.(1) Significantly elevated serum TNF-alpha was found in the women with GDM (5.2 +/- 1.6) ng/L as compared with the healthy pregnant women in third trimester (4.5 +/- 0.5) ng/L (P < 0.01); ISI between the two groups was significantly different, (-4.3 +/- 0.5) and (...3.8 +/- 0.3) (P < 0.01). (2) fasting plasma glucose, insulin, C-peptide, HbA1c in GDM group were (5.5 +/- 0.7) mmol/L, (13.4 +/- 3.8) mU/L, (1.6 +/- 0.4) nmol/L, (5.6 +/- 0.5)%, being significantly higher than those in the normal pregnant women (P < 0.01 or P < 0.05). (3) Significant negative linear correlation was revealed between TNF-alpha and ISI (r = -0.703, P < 0.01), and positive linear correlations between TNF-alpha and plasma glucose, C-peptide, and HbA1c were found (r = 0.512, 0.629, 0.386); but no correlation between TNF-alpha and insulin was found in GDM group. In normal group the correlation between ISI and TNF-alpha was also found (r = -0.390, P < 0.05), but less significant than that in the GDM group.Fasting plasma TNF-alpha levels in pregnant women with GDM is significantly higher than in normal pregnant women. A negative relationship between TNF-alpha and insulin sensitivity index is found in GDM, suggesting increased TNF-alpha may contribute to insulin resistance in pregnant women with gestational diabetes." @default.
- W2376457453 created "2016-06-24" @default.
- W2376457453 creator A5001288918 @default.
- W2376457453 creator A5012327060 @default.
- W2376457453 creator A5050687436 @default.
- W2376457453 creator A5066366965 @default.
- W2376457453 creator A5086654731 @default.
- W2376457453 date "2004-11-01" @default.
- W2376457453 modified "2023-10-18" @default.
- W2376457453 title "[Maternal serum tumor necrosis factor-alpha concentration and correlation with insulin resistance in gestational diabetes]." @default.
- W2376457453 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15634497" @default.
- W2376457453 hasPublicationYear "2004" @default.
- W2376457453 type Work @default.
- W2376457453 sameAs 2376457453 @default.
- W2376457453 citedByCount "5" @default.
- W2376457453 countsByYear W23764574532014 @default.
- W2376457453 countsByYear W23764574532022 @default.
- W2376457453 crossrefType "journal-article" @default.
- W2376457453 hasAuthorship W2376457453A5001288918 @default.
- W2376457453 hasAuthorship W2376457453A5012327060 @default.
- W2376457453 hasAuthorship W2376457453A5050687436 @default.
- W2376457453 hasAuthorship W2376457453A5066366965 @default.
- W2376457453 hasAuthorship W2376457453A5086654731 @default.
- W2376457453 hasConcept C126322002 @default.
- W2376457453 hasConcept C134018914 @default.
- W2376457453 hasConcept C17991360 @default.
- W2376457453 hasConcept C2777391703 @default.
- W2376457453 hasConcept C2778376644 @default.
- W2376457453 hasConcept C2779234561 @default.
- W2376457453 hasConcept C2779306644 @default.
- W2376457453 hasConcept C2779434492 @default.
- W2376457453 hasConcept C2780221984 @default.
- W2376457453 hasConcept C46973012 @default.
- W2376457453 hasConcept C54355233 @default.
- W2376457453 hasConcept C555293320 @default.
- W2376457453 hasConcept C71924100 @default.
- W2376457453 hasConcept C86803240 @default.
- W2376457453 hasConceptScore W2376457453C126322002 @default.
- W2376457453 hasConceptScore W2376457453C134018914 @default.
- W2376457453 hasConceptScore W2376457453C17991360 @default.
- W2376457453 hasConceptScore W2376457453C2777391703 @default.
- W2376457453 hasConceptScore W2376457453C2778376644 @default.
- W2376457453 hasConceptScore W2376457453C2779234561 @default.
- W2376457453 hasConceptScore W2376457453C2779306644 @default.
- W2376457453 hasConceptScore W2376457453C2779434492 @default.
- W2376457453 hasConceptScore W2376457453C2780221984 @default.
- W2376457453 hasConceptScore W2376457453C46973012 @default.
- W2376457453 hasConceptScore W2376457453C54355233 @default.
- W2376457453 hasConceptScore W2376457453C555293320 @default.
- W2376457453 hasConceptScore W2376457453C71924100 @default.
- W2376457453 hasConceptScore W2376457453C86803240 @default.
- W2376457453 hasIssue "11" @default.
- W2376457453 hasLocation W23764574531 @default.
- W2376457453 hasOpenAccess W2376457453 @default.
- W2376457453 hasPrimaryLocation W23764574531 @default.
- W2376457453 hasRelatedWork W138803513 @default.
- W2376457453 hasRelatedWork W1986132654 @default.
- W2376457453 hasRelatedWork W1991634670 @default.
- W2376457453 hasRelatedWork W2010140898 @default.
- W2376457453 hasRelatedWork W2022350198 @default.
- W2376457453 hasRelatedWork W2044146098 @default.
- W2376457453 hasRelatedWork W2132623660 @default.
- W2376457453 hasRelatedWork W2367639481 @default.
- W2376457453 hasRelatedWork W2378290744 @default.
- W2376457453 hasRelatedWork W2912657293 @default.
- W2376457453 hasVolume "39" @default.
- W2376457453 isParatext "false" @default.
- W2376457453 isRetracted "false" @default.
- W2376457453 magId "2376457453" @default.
- W2376457453 workType "article" @default.