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- W2376468932 abstract "Objective Estrogenic activity of animal-origin food in a city was studied to comprehensively evaluate the pollution by environmental estrogen.Methods The analysis was carried out through the combination of the recombinant yeast estrogen screen(YES) and high performance liquid chromatography-Tandem mass spectrometry(LC-MS/MS) method.Results The results obtained from the YES were expressed as biological estradiol equivalent(EEQbio),which ranged from 6.11 to 25.45 ng/g.In addition,17β-estradiol(E2) and bisphenol A(BPA) were detected in all samples by the LC-MS/MS.17α-ethinylestradiol(EE2) was also detected in most of the samples,and the concentration range was(2.87~5.05) ng/g,(0.48~3.57) ng/g and(1.23~7.38) ng/g respectively.The chemical estradiol equivalent(EEQchem) of samples calculated from the chemical method ranged from 3.15 to 15.14 ng/g.There was some correlation of the estradiol equivalent values measured by the YES and the LC-MS/MS(R2=0.443).Conclusion Certain degree of estrogenic activity was detected in all the samples,and the combination of the biological experiment and chemical analysis could more effectively evaluate the overall effect and pollution status of the environmental estrogen in animal food." @default.
- W2376468932 created "2016-06-24" @default.
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- W2376468932 date "2012-01-01" @default.
- W2376468932 modified "2023-09-22" @default.
- W2376468932 title "Investigation on estrogenic activity in animal food in a city" @default.
- W2376468932 hasPublicationYear "2012" @default.
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