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- W2376475252 abstract "Objective To compare the clinical efficacy and safety between homemade and imported pulmonary surfactant(PS)replacement therapy in premature infants with respiratory distress syndrome(RDS).Methods 107 premature infants with RDS from May 2009 to October 2010 were divide into 3 groups.Group A(n=42)was given homemade PS and and assisted ventilation;Group B(n=37)was given imported PS and assisted ventilation;Group C(n=28) was only used assisted ventilation.Results ①The symptoms and signs of RDS were improved obviously and quickly after PS treatment(P0.05).②There was no significant difference in blood gas indexes between the 3 groups(P0.05).③The ventilator parameters of PIP in group A/B were lower than those in group C(P0.05)during 1~24 h after PS treatment.④The ventilator parameters of FiO2 in group A were lower than those in group C(P0.05)during 2~6 h after PS treatment(P0.05).⑤Thoracic X-ray showed that the lung diseases in group A/B was improved significantly during 2~6 h after PS treatment(P0.05).⑥There was no significant difference between the 3 groups in duration of assisted ventilation,time of hospital stay and complications,etc(P0.05).⑦There was no significant difference in repeated PS use between group A and group B(P0.05).Conclusion Homemade and imported PS have the same efficacy and safety for RDS in premature infants,and imported PS is more convenient." @default.
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- W2376475252 date "2012-01-01" @default.
- W2376475252 modified "2023-09-24" @default.
- W2376475252 title "Comparison of homemade and imported pulmonary surfactant replacement therapy in premature infants with respiratory distress syndrome" @default.
- W2376475252 hasPublicationYear "2012" @default.
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