Matches in SemOpenAlex for { <https://semopenalex.org/work/W2376491878> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2376491878 endingPage "8" @default.
- W2376491878 startingPage "1" @default.
- W2376491878 abstract "It is becoming increasingly critical to identify potential toxicities early in the development of new chemical entities, be they for the pharmaceutical or chemical industries. Our current approaches have limitations and the utility of animal data may not always ensure the safety of a chemical or pharmaceutical in humans. Predictive toxicology is often thought of in terms of in silico computational approaches. However, the concept of predictive toxicology has broader implications and in this context the chapters in this book discuss in silico, in vitro, and in vivo approaches that are being developed and applied in regard to toxicity prediction, and how these approaches may be integrated into modeling and simulation approaches for human hazard and risk assessment. Ultimately, it will be how we use and evaluate all of the data and approaches that will assist in making the breakthrough that is needed in assessing risks and improving the human safety of chemicals, and thereby reducing attrition of drug candidates due to safety issues and the potential human health hazards associated with chemical exposures. The various chapters in this book also reflect the growing need for improvements in our technologies and abilities to predict the toxicities of pharmaceutical and industrial chemicals to ensure product safety and the protection of public health. It brings together leading experts in the fields of toxicology and risk assessment to discuss their views on the current status of toxicity prediction as well as their visions of the future needs and challenges." @default.
- W2376491878 created "2016-06-24" @default.
- W2376491878 creator A5053275832 @default.
- W2376491878 date "2011-01-01" @default.
- W2376491878 modified "2023-09-27" @default.
- W2376491878 title "Chapter 1. Introduction and Overview" @default.
- W2376491878 doi "https://doi.org/10.1039/9781849733045-00001" @default.
- W2376491878 hasPublicationYear "2011" @default.
- W2376491878 type Work @default.
- W2376491878 sameAs 2376491878 @default.
- W2376491878 citedByCount "2" @default.
- W2376491878 countsByYear W23764918782019 @default.
- W2376491878 countsByYear W23764918782020 @default.
- W2376491878 crossrefType "book-chapter" @default.
- W2376491878 hasAuthorship W2376491878A5053275832 @default.
- W2376491878 hasConcept C112930515 @default.
- W2376491878 hasConcept C12174686 @default.
- W2376491878 hasConcept C127413603 @default.
- W2376491878 hasConcept C144133560 @default.
- W2376491878 hasConcept C151730666 @default.
- W2376491878 hasConcept C183696295 @default.
- W2376491878 hasConcept C18903297 @default.
- W2376491878 hasConcept C2522767166 @default.
- W2376491878 hasConcept C2779343474 @default.
- W2376491878 hasConcept C2987857752 @default.
- W2376491878 hasConcept C38652104 @default.
- W2376491878 hasConcept C41008148 @default.
- W2376491878 hasConcept C49261128 @default.
- W2376491878 hasConcept C539667460 @default.
- W2376491878 hasConcept C71924100 @default.
- W2376491878 hasConcept C86803240 @default.
- W2376491878 hasConcept C99454951 @default.
- W2376491878 hasConceptScore W2376491878C112930515 @default.
- W2376491878 hasConceptScore W2376491878C12174686 @default.
- W2376491878 hasConceptScore W2376491878C127413603 @default.
- W2376491878 hasConceptScore W2376491878C144133560 @default.
- W2376491878 hasConceptScore W2376491878C151730666 @default.
- W2376491878 hasConceptScore W2376491878C183696295 @default.
- W2376491878 hasConceptScore W2376491878C18903297 @default.
- W2376491878 hasConceptScore W2376491878C2522767166 @default.
- W2376491878 hasConceptScore W2376491878C2779343474 @default.
- W2376491878 hasConceptScore W2376491878C2987857752 @default.
- W2376491878 hasConceptScore W2376491878C38652104 @default.
- W2376491878 hasConceptScore W2376491878C41008148 @default.
- W2376491878 hasConceptScore W2376491878C49261128 @default.
- W2376491878 hasConceptScore W2376491878C539667460 @default.
- W2376491878 hasConceptScore W2376491878C71924100 @default.
- W2376491878 hasConceptScore W2376491878C86803240 @default.
- W2376491878 hasConceptScore W2376491878C99454951 @default.
- W2376491878 hasLocation W23764918781 @default.
- W2376491878 hasOpenAccess W2376491878 @default.
- W2376491878 hasPrimaryLocation W23764918781 @default.
- W2376491878 hasRelatedWork W1756451514 @default.
- W2376491878 hasRelatedWork W2080865512 @default.
- W2376491878 hasRelatedWork W2086034476 @default.
- W2376491878 hasRelatedWork W2094741178 @default.
- W2376491878 hasRelatedWork W2100245828 @default.
- W2376491878 hasRelatedWork W2121993387 @default.
- W2376491878 hasRelatedWork W2147695654 @default.
- W2376491878 hasRelatedWork W2196370775 @default.
- W2376491878 hasRelatedWork W2291344513 @default.
- W2376491878 hasRelatedWork W2414350704 @default.
- W2376491878 hasRelatedWork W2535167826 @default.
- W2376491878 hasRelatedWork W2585780224 @default.
- W2376491878 hasRelatedWork W2594548019 @default.
- W2376491878 hasRelatedWork W2756267483 @default.
- W2376491878 hasRelatedWork W2794565592 @default.
- W2376491878 hasRelatedWork W2904763666 @default.
- W2376491878 hasRelatedWork W3125070038 @default.
- W2376491878 hasRelatedWork W3205843050 @default.
- W2376491878 hasRelatedWork W3207168733 @default.
- W2376491878 hasRelatedWork W2317716815 @default.
- W2376491878 isParatext "false" @default.
- W2376491878 isRetracted "false" @default.
- W2376491878 magId "2376491878" @default.
- W2376491878 workType "book-chapter" @default.