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- W2376519602 abstract "Objective:The essay is meant to observe the effects of Guanxinping on the levels of TNF-α and IL-1 secreted by injured coronary vascular endothelial cell induced by H2O2 and to discuss possible mechanism of Guanxinping in treating coronary heart disease.Methods:Endothelial cells ECV304 were damaged with 100μmol/L H2O2,dividing cells into normal control group,model group,positive control group,low dose group,middle dose group and high dose group.Administration with serum pharmacological method was used to continue to observe the cells under a microscope,and detect levels of TNF-α and IL-1 then.Results:100μmol/L H2O2 could injure ECV304.Guanxinping significantly decreased levels of TNF-α and IL-1 secreted by injured coronary vascular endothelial cell.Conclusion:Guanxinping could reduce the damage of ECV304 induced by H2O2,the mechanism may be related to decreasing TNF-α and IL-1 levels,and regulating vascular endothelial inflammatory reaction." @default.
- W2376519602 created "2016-06-24" @default.
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- W2376519602 date "2011-01-01" @default.
- W2376519602 modified "2023-09-24" @default.
- W2376519602 title "Influence of Guanxinping on Levels of Inflammatory Factors of Injured Vascular Enclothelial Cells Induced by H_2O_2" @default.
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