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- W2376522427 abstract "Objective:To investigate the interference of plasma osmotic pressure increased caused by different kinds of solute in MCV detection in four different type cytoanalyzer,and then put forward the solve measures.Methods:Preparing hypertonic blood samples of certain osmotic pressure caused by difference kinds of solution,determining the MCV of samples by Sysmex XE-2100,XS-1000i,Beckman Coulter LH750 and Mindray BC-3000PLUS(whole blood mode),and by BC-3000PLUS(predilute mode),comparing the results in different detecting mode.Results:The high plasma osmotic pressure caused by glucose would lead to the artefactual erythrocyte swelling(maximum CV is 63.04%).And the rise caused by sodium chloride or urea would not show an obvious effect in MCV detection(CV1.5%).The sensitivity of the artefactual increase in MCV measurements was as fallows: XS-1000iXE-2100LH750BC-3000PLUS.After prediluting and placing the samples for 10 minutes,the measurements returned to normal.Conclusion:The hypertonic pressure caused by hyperglycemia will lead to the artefactual increase of the MCV measurements by the cytoanalyzer.Therefore the samples should be prediluted and are measured again before reporting." @default.
- W2376522427 created "2016-06-24" @default.
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- W2376522427 date "2010-01-01" @default.
- W2376522427 modified "2023-09-23" @default.
- W2376522427 title "Influence of Plasma Osmotic Pressure Rise in MCV Detection with Different Type Cytoanalyzer" @default.
- W2376522427 hasPublicationYear "2010" @default.
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