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- W2376551968 abstract "Objective To investigate the oxidative stress status in subjects with impaired glucose tolerance (IGT).Methods The fasting serum levels of reduced glutathione hormone (GSH),superoxide dismutase (SOD),reactive oxygen species (ROS),malonaldehyde (MDA),were determined in 45 subjects with IGT and 51 subjects with normal glucose tolerant(NGT).Results The fasting serum levels of GSH and SOD were significantly lower in subjects with IGT than those in subjects with NGT (P0.05),the fasting serum levels of ROS and MDA were significantly higher in subjects with IGT than those in subjects with NGT (P0.05),and after adjusting for age and sex,there were still stastically significant difference between IGT and NGT(P0.05).Spearman analysis shows that the serum GSH level in IGT was significantly correlated with age,BMI,FBG and TG; the serum SOD level in IGT was significantly correlated with age,FBG,HOMA-IR and TC; the serum ROS level in IGT was significantly correlated with age,BMI,FBG,HOMA-IR and TG; the serum MDA level in IGT was significantly correlated with HOMA-IR and TG.Conclusions This study suggests that there are high level of oxidative stress status in subjects with IGT,but this remains to be further study of larger samples to confirm." @default.
- W2376551968 created "2016-06-24" @default.
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- W2376551968 date "2010-01-01" @default.
- W2376551968 modified "2023-09-28" @default.
- W2376551968 title "High level of oxidative stress status in subjects with impaired glucose tolerance" @default.
- W2376551968 hasPublicationYear "2010" @default.
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