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- W2376552020 abstract "Objective To study the effects of oxymattine(OMT) on left ventricular remodeling after myocardial infarction(MI) in rats.Methods The MI models were established by ligation of the left anterior descending coronary artery in 24 SD rats,which were divided into model group and three OMT intervention groups.The rats in OMT groups were given three different doses of OMT by direct gastric gabage for 8 weeks.Another 6 rats were taken as the sharm controls.Eight weeks later,the extent of myocardial remodeling with the myocardial remodeling index,collagen content and histopathological cganges were examined.Results Compared to the sham controls,significant changes in the myocardial remodeling were seen in model group(P0.01),which were significantly lower in OMT groups,especially with high dose OMT,than those in model group(P0.05 or P0.01).Conclusion Oxymatrine has some protective effects on the myocardial remodeling." @default.
- W2376552020 created "2016-06-24" @default.
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- W2376552020 date "2010-01-01" @default.
- W2376552020 modified "2023-09-24" @default.
- W2376552020 title "Effects of oxymattine on left ventricular remodeling after acute myocardial infarction in rats" @default.
- W2376552020 hasPublicationYear "2010" @default.
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