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- W2376568990 abstract "Objective:To study the significance of early diagnosis and differential diagnosis of epithelial ovarian tumors with Color Doppler Sonography integrating vascular endothelial growth factor(VEGF) and microvessel density(MVD).Methods:Sixty-two patients with clinically suspected epithelial ovarian neoplasm were evaluated by Color Doppler sonography,and were confirmed by operation and pathology.Of the total,epithelial ovarian cancer(the malignant group,n=31) and ovarian benign tumors(the optimum group,n=31),were observed for the characteristic of morphologic construction and hemodynamics of ovarian tumors.The expression of VEGF was measured by enzyme linked immunosorbent assay(ELISA)before operation.Tumors' MVD were examined by immunization histological chemistry after operation.Results:Malignant tumors were more likely to have either complex or solid echogenic pattern,in which color flow was abundantly found in the tumors and was main of arterioles with low impedance.Benign tumors were more likely to have cystic echogenic pattern or solid echogenic pattern with regular borders,and the dominance was blood flow with high impedance around the tumors.There were significant differences with resistent index(RI) between malignant group and benign group(P0.01).The expression of serum VEGF in the malignant group was significantly higher than the benign group(P0.01).The malignant groups' MVD were higher than the benign groups'(P0.01).The expression of serum VEGF in the groups of RI0.4 was obviously higher than the RI≥0.4 group(P0.01).The RI0.4 groups' MVD was significantly higher than the RI≥0.4 groups'(P0.01).Conclusion:Color Doppler Sonography integrating VEGF and MVD has important significance in early diagnosis and differential diagnosis of epithelial ovarian tumors.It is possibly to develop a new way of diagnosis and prognosis of epithelial ovarian carcinoma." @default.
- W2376568990 created "2016-06-24" @default.
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- W2376568990 date "2009-01-01" @default.
- W2376568990 modified "2023-09-26" @default.
- W2376568990 title "The diagnosis significance of epithelial ovarian tumors with Color Doppler Sonography integrating VEGF and MVD" @default.
- W2376568990 hasPublicationYear "2009" @default.
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