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- W2376571263 abstract "Objective:To evaluate the value of proton magnetic resonance spectroscopy (1H-MRS)in the localization diagnosis (LD) of temporal lobe epilepsy (TLE).Methods:15 selected patients with TLE verified by operation and pathology and 15 healthy volunteers were studied,spectra were obtained in the region of both temporal lobes separately and exact localization was performed in the region of both hippocampuses.The values of N-acetylaspartate (NAA),Creatine (Cr) and Choline (Cho) were calculated by integration of their peaks,and the relative ratios of them were analyzed.The diagnostic value of 1H-MRS for the LD of TLE was analyzed.Results:It was very good that there exists a consistency of hippocampus sclerosis diagnosis between two radiologists.The value of K was 0.80 according to Kappa test.MRI abnormalities were found in 10 cases.The ipsilateral group of TLE patients had lower ratios of NAA/(Cho+Cr),and the differences compared with those of the normal group and contra-lateral subgroup were statistically significant (F=23.170,P0.05).1H-MRS was positive in 12 cases and negative in the other 3 cases.Combination of 1H-MRS with MRI can make the accuracy cases of LD raising to 13.Conclusion:1H-MRS is sensitive to the neuron abnormality.It provides a new method for the LD of TLE.Combination of MRS with MRI can improve the accuracy ratio of the LD." @default.
- W2376571263 created "2016-06-24" @default.
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- W2376571263 date "2007-01-01" @default.
- W2376571263 modified "2023-09-22" @default.
- W2376571263 title "Evaluation of Proton Magnetic Resonance Spectroscopy for Localization of Temporal Lobe Epilepsy" @default.
- W2376571263 hasPublicationYear "2007" @default.
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