Matches in SemOpenAlex for { <https://semopenalex.org/work/W2376572743> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2376572743 abstract "Objective:To study the pharmacokinetics of pantoprazole(Pan)enantiomers in rats.Methods:A 7 h blood collection was done after rats administrating racemic Pan at a dose of 5 mg·kg~(-1)by intragastric administra- tion.The plasma concentrations of Pan were measured by chiral stationary phase HPLC method(CSP-HPLC)with a mobile phase consisted of 100 mmol·L~(-1)sodium phosphate buffer(pH 5.5)-acetonitrile(70:30).Results: The disposition of l-Pan and d-Pan was conformed to two-compartment model by 3P87 program.Maximal plas- ma concentration(C_(max)):1-Pan was(1.63±1.22)μg·mL~(-1),d-Pan was(2.17±1.33)μg·mL~(-1).Area un- der blood concentration-time(AUC_(0→∞)):l-Pan was(2.89±1.54)μg·h·mL~(-1),d-Pan was(2.69±1.60) μg·h·mL~(-1).The biological half life(T_(1/2)):l-Pan was(6.42±2.70)h,d-Pan was(0.65±0.26)h.Conclu- sion:The results indicate that the pharmacokinetics of pantoprazole enantiomers has an.stereoselective character in rats." @default.
- W2376572743 created "2016-06-24" @default.
- W2376572743 creator A5056277137 @default.
- W2376572743 date "2006-01-01" @default.
- W2376572743 modified "2023-09-25" @default.
- W2376572743 title "Pharmacokinetics study of pantoprazole enantiomers in rats" @default.
- W2376572743 hasPublicationYear "2006" @default.
- W2376572743 type Work @default.
- W2376572743 sameAs 2376572743 @default.
- W2376572743 citedByCount "0" @default.
- W2376572743 crossrefType "journal-article" @default.
- W2376572743 hasAuthorship W2376572743A5056277137 @default.
- W2376572743 hasConcept C112705442 @default.
- W2376572743 hasConcept C161790260 @default.
- W2376572743 hasConcept C179998833 @default.
- W2376572743 hasConcept C181647583 @default.
- W2376572743 hasConcept C185592680 @default.
- W2376572743 hasConcept C2777498785 @default.
- W2376572743 hasConcept C2781315423 @default.
- W2376572743 hasConcept C43617362 @default.
- W2376572743 hasConcept C486523 @default.
- W2376572743 hasConcept C55493867 @default.
- W2376572743 hasConcept C71240020 @default.
- W2376572743 hasConcept C71924100 @default.
- W2376572743 hasConcept C96616956 @default.
- W2376572743 hasConcept C98274493 @default.
- W2376572743 hasConceptScore W2376572743C112705442 @default.
- W2376572743 hasConceptScore W2376572743C161790260 @default.
- W2376572743 hasConceptScore W2376572743C179998833 @default.
- W2376572743 hasConceptScore W2376572743C181647583 @default.
- W2376572743 hasConceptScore W2376572743C185592680 @default.
- W2376572743 hasConceptScore W2376572743C2777498785 @default.
- W2376572743 hasConceptScore W2376572743C2781315423 @default.
- W2376572743 hasConceptScore W2376572743C43617362 @default.
- W2376572743 hasConceptScore W2376572743C486523 @default.
- W2376572743 hasConceptScore W2376572743C55493867 @default.
- W2376572743 hasConceptScore W2376572743C71240020 @default.
- W2376572743 hasConceptScore W2376572743C71924100 @default.
- W2376572743 hasConceptScore W2376572743C96616956 @default.
- W2376572743 hasConceptScore W2376572743C98274493 @default.
- W2376572743 hasLocation W23765727431 @default.
- W2376572743 hasOpenAccess W2376572743 @default.
- W2376572743 hasPrimaryLocation W23765727431 @default.
- W2376572743 hasRelatedWork W2046813999 @default.
- W2376572743 hasRelatedWork W2060498821 @default.
- W2376572743 hasRelatedWork W2066833272 @default.
- W2376572743 hasRelatedWork W2170281823 @default.
- W2376572743 hasRelatedWork W2347583713 @default.
- W2376572743 hasRelatedWork W2353858057 @default.
- W2376572743 hasRelatedWork W2354638627 @default.
- W2376572743 hasRelatedWork W2355657428 @default.
- W2376572743 hasRelatedWork W2363726788 @default.
- W2376572743 hasRelatedWork W2375963104 @default.
- W2376572743 hasRelatedWork W2377959917 @default.
- W2376572743 hasRelatedWork W2380590890 @default.
- W2376572743 hasRelatedWork W2380750272 @default.
- W2376572743 hasRelatedWork W2382454464 @default.
- W2376572743 hasRelatedWork W2389434322 @default.
- W2376572743 hasRelatedWork W2390955023 @default.
- W2376572743 hasRelatedWork W2393439238 @default.
- W2376572743 hasRelatedWork W2393681713 @default.
- W2376572743 hasRelatedWork W2398889101 @default.
- W2376572743 hasRelatedWork W2418957636 @default.
- W2376572743 isParatext "false" @default.
- W2376572743 isRetracted "false" @default.
- W2376572743 magId "2376572743" @default.
- W2376572743 workType "article" @default.