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- W2376579996 abstract "Objective To summarize the usage of green fluorescent protein(GFP) in drug design and screening which in an important part of drug research.Methods In this paper,22 Chinese and English articles are used to review what GFP is and its applications in drug discovery.Results Green fluorescent protein found in jellyfish(Aequorea victoria),was such a type of protein that under UV,it could give a visible and green light.In recent years,GFP had been widely used in biochemical,cell-biological and medical sciences,as it played the role of live sensor.It owns excellent stability towards chemical reagents such as acid,alkali, oxidant and reducing agent;therefore,it is a good label molecule in vivo to monitor gene expression,intracellular protein localization,cancer cell's living process,etc.Conclusions With the ability to monitor the reaction of life,GFP has an important value for assisted drag design and the establishment of drug screening model.Combination of GFP and drug design and screening will inject new vitality for new drug research and development." @default.
- W2376579996 created "2016-06-24" @default.
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- W2376579996 date "2013-01-01" @default.
- W2376579996 modified "2023-09-23" @default.
- W2376579996 title "Application progress of green fluorescent protein in drug discovery" @default.
- W2376579996 hasPublicationYear "2013" @default.
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