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- W2376606906 abstract "Objective To study the change of immune function in rats with imPlanted breast cancer after Ar-He cryoblation.Methods A total of 40 SD rats were randomized into 4 groups:cryoblation,surgical resection,tumor-bearing control group,and normal control group.The contents of T cell Phenotype in blood were detected with flow cytometry(FCM) and the contents of sIL-2R were measured by ELISA before and after cryoblation.Results Before cryoblation,CD3+、CD4+、CD8+ T cell、CD4+ /CD8+ and sIL-2R in the group of tumor-bearing control rats were significantly different than those in the normal control group.After cryoblation,CD3+、CD4+、CD4+ /CD8+ in the cryoblation rats model increased significantly(P0.05)compared with the group of tumor-bearing control,and it showed significantly different(P0.05)and CD8+T cell、expression of sIL-2R decreased.It also showed significantly different compaved with the group of surgical resection after 1,3 weeks(P0.05).Conclusion Cryoblation can efficiently stimulate splenocyte activation and Proliferation in tumor-bearing mice,and enhance splenocyte cytotoxicity to tumor cells.cryoblation may activate and improve cell-mediate immune function to some extent." @default.
- W2376606906 created "2016-06-24" @default.
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- W2376606906 date "2010-01-01" @default.
- W2376606906 modified "2023-09-23" @default.
- W2376606906 title "Alteration of immune function of rats with implanted breast cancer after Ar-He cryoblation" @default.
- W2376606906 hasPublicationYear "2010" @default.
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