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- W2376607526 abstract "Registries characterize the effectiveness and safety of therapeutic interventions in daily clinical practice. Data from registries enable mining the records of tens of thousands of patients towards determining the effectiveness, safety, and cost-benefit of any given therapeutic. The strengths of registries include real-life settings, greater power than clinical trials to detect rare events, and the study of multiple outcomes and several research questions. Registries also have their weaknesses. They are expensive, less accurate than clinical trials, affected by channelling bias, often require links to external sources or use historic and selected control cohorts or combine datasets to increase power, and have the risk of multiple confounders. Since the beginning of biological era, registries were developed to profile emerging treatments. This article reviews the role of registries in the treatment of rheumatoid arthritis with biologic disease-modifying anti-rheumatic drugs." @default.
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- W2376607526 date "2009-04-01" @default.
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- W2376607526 title "Les arthroplasties de hanche aujourd’hui : principaux matériaux, voies d’abord" @default.
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- W2376607526 doi "https://doi.org/10.1016/j.rhum.2008.04.026" @default.
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