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- W2376656875 abstract "Mesenchymal stem cells(MSCs)are a kind of adult stem cells with low immunogenic and able to exert immunomodu- latory function by various approaches, such as suppression of lymphocyte proliferation through the mixed lymphocyte reaction, reduction of the dentritic cell generation, maturation and function, inhibition NK activity, down-regulation of the CTL formation and enhancement of regulatory T-cell proportion. In vivo experiments show that MSCs infusion can prolong the survival time of allogeneic skin graft in ba- boon, but aggravation of acute rejection of heart allograft in mice, clinical reports have been documented about clinical application of M SC in the management of graft-versus-host disease In this review, the immunological characteristics and the immunomodulation functions vitro an d in vivo of MSCs were summarized." @default.
- W2376656875 created "2016-06-24" @default.
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- W2376656875 date "2008-01-01" @default.
- W2376656875 modified "2023-09-23" @default.
- W2376656875 title "Advancement in Research on Immunomodulatory Function of Mesenchymal Stem Cells" @default.
- W2376656875 hasPublicationYear "2008" @default.
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