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- W2376698845 abstract "Activins, which consist of two disulfide-linked β subunits, are members of the transforming growth factor β (TGF-β) superfamily of growth factors. Four mammalian activin β subunits, termed as βA, βB, βC, and βE respectively, have been identified. Activin A, the homodimer of two βA subunits, is a pleiotropic cytokine and is expressed in many tissues and cells. There has been compelling evidence that activin A is involved in the regulation of reproductive biology, embryonic development, erythroid differentiation, systemic inflammation, induced apoptosis, tissue repair, fibrogenesis and so on, through classic activin signaling pathway. βC and βE subunits, which are almost exclusively expressed in the liver, are still quite incompletely understood. In this review, we summarize and discuss the function of βC and βE subunits in liver. Further research should be made to understand the biological role of the βC and βE subunits." @default.
- W2376698845 created "2016-06-24" @default.
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- W2376698845 date "2008-01-01" @default.
- W2376698845 modified "2023-09-24" @default.
- W2376698845 title "Advances in research of activins C and E" @default.
- W2376698845 hasPublicationYear "2008" @default.
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