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- W2376768145 abstract "Objective:to understand immuisolation effect o f Alginate polylysine alginate(APA) in vitro. Materials: Che cking the diffusion through APA microcapsule membrane of IgG labeled with fluo rescein by laser scan confocal microscope(LSCM). Assessing injury effect of NK c ells to K562 or encapsulated K562. Assessing protection effect of APA microcapsu le from mouse spleen lymphocyte proliferation stimulated by BCCs. Checking injur y effect of IL 2 and TNF αto cells or microencapsulated cells. Result s: IgG can not go through into APA microcapsule.NK cells have cytotoxic effect to K562 cells and APA can protect K562 from attack of NK. APA can prevent mouse spleen lymphocyte proliferation stimulated by BCCs.IL 2 can pass through APA membrane and support existence of CTLL cells. TNF αcan pass through APA m embrane and kill L929 cells. Conclusion: APA microcapsule can re markablely prevent cell mediated and antigen mediated immunologic reactions." @default.
- W2376768145 created "2016-06-24" @default.
- W2376768145 creator A5018702285 @default.
- W2376768145 date "2003-01-01" @default.
- W2376768145 modified "2023-09-23" @default.
- W2376768145 title "Determination of immuisolation effect of APA microcapsules in vitro" @default.
- W2376768145 hasPublicationYear "2003" @default.
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