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- W2376780648 abstract "Objective To study the effect of Interferon-γ(IFN-γ) on preventing relapse of condyloma acuminatum (CA). Method Seventy-six patients were diagnosed as CA. The patients having connective tissue disease, allergic disease, serious systematic disease, other virus disease, immuno-modulatory drug or immuno-suppressive drug to be used in one year were excluded. The rash of all patients were eliminated with electrofulguration. The patients were divided into two groups: IFN-γ and control. Thirty-eight cases of patients with CA were treated with IFN-γ and were compared with 38 patients treated with PolyI:C. The T-cell subpopulation (CD 3、CD 4、CD 8) in peripheral blood of patients treated with IFN-γ were determined by APAAP before electrofulguration and after therapy. All the patients were followed-up for 6 months. Results The results showed that the relapse rate was 15 8% in IFN-γ group, while it was 36 8% in the control in 6 months after therapy. In 32 patients, who had no relapse in 6 months after therapy, the T-cell recovered to normal. While there was no significant change in 6 patients with relapse in 6 months after therapy. Conclusion It indicates that the relapse rate of the therapy group is significantly lower than the control (χ 2=4 34,P0 05). IFN-γ is a cell factor effective to prevent and cure CA." @default.
- W2376780648 created "2016-06-24" @default.
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- W2376780648 date "2001-09-20" @default.
- W2376780648 modified "2023-09-26" @default.
- W2376780648 title "Analysis of Effect of Interferon-γon Preventing Relapse ofCondyloma Acuminatum" @default.
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