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- W2376804979 abstract "Three stable hybridoma cell lines(AHros,AHAICI and AHnCI)secreting monoclonalanhbodies against human free lambda chains were obtained by fusion of SpZ/0 cells with splenocytesof BALB/c miCe bomunized with mixed pure lambda Bence--Jones proteins.All these McAbsshowed strong reachon with all 17 lambda Benocjones proteins isolated by us from different multiplemyeloma PatientS, but no reaction with combined lambda chains a7.i kappa chains.These results suggested that the 3 McAbs seem to be against common antigenic determinant of human free lambdachains. They all belonged to IgGI subclass and reacted with the same epitope. The preliminary testSshowed that these McAbs were good in both specificity and sensitivity for detection of free lambdachains in serum and urine of normal human and multiple myeloma Patients.Some problems ofinununization were discussed." @default.
- W2376804979 created "2016-06-24" @default.
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- W2376804979 date "1995-01-01" @default.
- W2376804979 modified "2023-09-26" @default.
- W2376804979 title "Studies on the Preparing Series of McAbs against Human Ig Light Chains III.Production and preliminary Characterization of Monoclonal Antibodies against Common Antigenic Determinant of Human Ig Free Lambda Chains" @default.
- W2376804979 hasPublicationYear "1995" @default.
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