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- W2376810410 abstract "Objective To review the false-negative cases in cervical thinprep liquid based cytologic test(TCT)and analyze the causes of the false negative reports.Methods The results of patients who had simultaneously taken the cervical TCT and high-risk human papilloma virus test(HR-HPV)and localization biopsy by vaginoscopy were all recorded.The results of 18 cases with negative in TCT but positive in biopsy diagnosis were retrospectively analyzed.Cells amount,endocervical column cells,metaplastic cells,smear with blood cells,serious inflammation and distance from the lesion to endocervical tube were recorded in all the cases.Results The positive cases after review,cellular rate less than 40%,absence of endocervical transformation zone,stain with blood cell,serious inflammation and distance from the lesion to endocervical tube were 5.56%,11.11%,44.44%,24.67%,11.11%,5.56% respectively among the false-negative cases.The false negative rate of TCT was higher than that of TCT plus HR-HPV that the difference was statistically significant between them(P0.05).Conclusion The standard specimens,the improvement of physician's film-reading skill in diagnosis and the application of the perfect technologies,such as adding computer-assisted cytologic test system after TCT or TCT plus HR-HPV DNA test can reduce the false negative rate.It's important that gynecologists do multiple biopsies under vaginoscope to the patients who are suspicious of cancer but negative cytology." @default.
- W2376810410 created "2016-06-24" @default.
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- W2376810410 date "2011-01-01" @default.
- W2376810410 modified "2023-09-26" @default.
- W2376810410 title "The result analysis about the false-negative report of cervical ThinPrep cytologic test" @default.
- W2376810410 hasPublicationYear "2011" @default.
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