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- W2376813376 abstract "Objective To study the effects of activation of death receptor signaling pathways on cell membrane in the process of apoptosis induced by ionizing radiation. Methods The BET-2 cells were radiated with 0、1、3、5、7、10Gy and divided into control group and caspase-8-specific inhibitor IETD-fmk-treated group. Apoptosis were measured by Annexin-V staining, caspase-8 and caspase-3 were determined at different time phases after irradiation. Results Apoptosis was induced and caspase-8 and caspase-3 were increased in a pattern of dose-effect and time-course after irradiation and decreased after treated with IETD-fmk partly. Conclusions Apoptosis was induced by activation of the death receptor signaling pathways on cell membrane after ionizing radiation directly." @default.
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- W2376813376 date "2006-01-01" @default.
- W2376813376 modified "2023-09-23" @default.
- W2376813376 title "The Activation of Death Receptor Signaling Pathways on Cell Membrane by Ionizing Radiation Activaties" @default.
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