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- W2376824203 abstract "[Objective] To study the hypoglycemic activity and the effect on oral glucose tolerance test(OGTT) of polysaccharides from Tremella Aurantialba mycelium(TMP) in experimental diabetic mice induced by alloxan.[Method] The anti-hyperglycemic effect of TMP was investigated in diabetic female mice induced by alloxan.The mice were divided into 4 groups,which were low-dose group(50 mg/kg),middle-dose group(100 mg/kg),high-dose group(150 mg/kg) and diabetic model control group.And the normal control group was also established.Fed with TMP by intragastric administration for 28 d,the hypoglycemic effect and OGTT were tested.[Result] Compared with model group,the body weight of low-,middle-and high-dose groups increased significantly(P0.05).The serum glucose value of high-dose group decreased obviously by 15.4%(P0.05).In OGTT,compared with model control group,the values of serum glucose after fed with glucose for 0.5 and 2 h were reduced by 9.4%(P0.05) and 12.8%(P0.05) respectively.The area of glucose curve declined by 10.3%(P0.05).[Conclusion] TMP fed with 150 mg/kg had obvious hypoglycemic activity and the ability of glucose tolerance.TMP fed with 50,100 and 150 mg/kg could decrease the weight losing of diabetic mice." @default.
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- W2376824203 date "2012-01-01" @default.
- W2376824203 modified "2023-09-25" @default.
- W2376824203 title "Hypoglycemic Activity of Polysaccharides Extracted from Tremella Aurantialba Mycelium in Experimental Diabetic Mice" @default.
- W2376824203 hasPublicationYear "2012" @default.
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