Matches in SemOpenAlex for { <https://semopenalex.org/work/W2376875006> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2376875006 abstract "Objective To detect aberrant methylation status of the 5'CpG island locating in the promoter area of pl6 in pancreatic cancer, the relationship between the aberrant methylation of p16 and clinical manifestation was analyzed. Methods Target DNA was modified by bisulfit, and p16 fragment was amplified with primers specific for methylated and unmethylated DNA. Results Aberrant methylation of 5'CpG island locating in the promoter area of pl6 was detected in 14/36 cases of pancreatic cancer, and no aberrant methylated p16 sequences were detected in tissue adjacent to cancer (5 cases), normal pancreatic tissue (1 case), pancreatitis (7 cases) and pancreatic mucinous cystoadenocarcinima (2 cases). Conclusions Methylation of pl6 gene promoter 5'CpG island can induce inactivation of pl6 gene and the methylation can be detected in pancreatic cancer. Detection of aberrant p16 methylation may be helpful to the diagnosis of pancreatic cancer." @default.
- W2376875006 created "2016-06-24" @default.
- W2376875006 creator A5017777338 @default.
- W2376875006 date "2002-01-01" @default.
- W2376875006 modified "2023-09-23" @default.
- W2376875006 title "Detection of aberrant p16 methylation in pancreatic cancer by MSP and its clinical significance" @default.
- W2376875006 hasPublicationYear "2002" @default.
- W2376875006 type Work @default.
- W2376875006 sameAs 2376875006 @default.
- W2376875006 citedByCount "0" @default.
- W2376875006 crossrefType "journal-article" @default.
- W2376875006 hasAuthorship W2376875006A5017777338 @default.
- W2376875006 hasConcept C104317684 @default.
- W2376875006 hasConcept C121608353 @default.
- W2376875006 hasConcept C140173407 @default.
- W2376875006 hasConcept C150194340 @default.
- W2376875006 hasConcept C153911025 @default.
- W2376875006 hasConcept C190727270 @default.
- W2376875006 hasConcept C2780210213 @default.
- W2376875006 hasConcept C33288867 @default.
- W2376875006 hasConcept C502942594 @default.
- W2376875006 hasConcept C54355233 @default.
- W2376875006 hasConcept C86803240 @default.
- W2376875006 hasConceptScore W2376875006C104317684 @default.
- W2376875006 hasConceptScore W2376875006C121608353 @default.
- W2376875006 hasConceptScore W2376875006C140173407 @default.
- W2376875006 hasConceptScore W2376875006C150194340 @default.
- W2376875006 hasConceptScore W2376875006C153911025 @default.
- W2376875006 hasConceptScore W2376875006C190727270 @default.
- W2376875006 hasConceptScore W2376875006C2780210213 @default.
- W2376875006 hasConceptScore W2376875006C33288867 @default.
- W2376875006 hasConceptScore W2376875006C502942594 @default.
- W2376875006 hasConceptScore W2376875006C54355233 @default.
- W2376875006 hasConceptScore W2376875006C86803240 @default.
- W2376875006 hasLocation W23768750061 @default.
- W2376875006 hasOpenAccess W2376875006 @default.
- W2376875006 hasPrimaryLocation W23768750061 @default.
- W2376875006 hasRelatedWork W1916393181 @default.
- W2376875006 hasRelatedWork W1986554125 @default.
- W2376875006 hasRelatedWork W2024552817 @default.
- W2376875006 hasRelatedWork W2124411673 @default.
- W2376875006 hasRelatedWork W2156447474 @default.
- W2376875006 hasRelatedWork W2188689241 @default.
- W2376875006 hasRelatedWork W2349152365 @default.
- W2376875006 hasRelatedWork W2357993890 @default.
- W2376875006 hasRelatedWork W2358543608 @default.
- W2376875006 hasRelatedWork W2368875551 @default.
- W2376875006 hasRelatedWork W2370059759 @default.
- W2376875006 hasRelatedWork W2370409112 @default.
- W2376875006 hasRelatedWork W2372857642 @default.
- W2376875006 hasRelatedWork W2384450213 @default.
- W2376875006 hasRelatedWork W2385477090 @default.
- W2376875006 hasRelatedWork W2385741739 @default.
- W2376875006 hasRelatedWork W2389531624 @default.
- W2376875006 hasRelatedWork W2921090022 @default.
- W2376875006 hasRelatedWork W3029338308 @default.
- W2376875006 hasRelatedWork W229508786 @default.
- W2376875006 isParatext "false" @default.
- W2376875006 isRetracted "false" @default.
- W2376875006 magId "2376875006" @default.
- W2376875006 workType "article" @default.