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- W2376877572 abstract "The objective of the present study was to study the antihyperglycemic effects of flavonoids from methanolic extract of aerial parts of Scoparia dulcis leaves in normal, glucose loaded and streptozotocin induced diabetic rats. The methanolic extract of S. dulcis at a dose of 100, 200, 400 mg/kg of body weight (p.o) and standard drug glibenclamide 500 μg/kg, in all three animal models. The extract exhibited significant hypoglycemic activity in all three animal models when compared with a standard antidiabetic agent Glibenclamide. The hypoglycemia produced by the extract may be due to increased uptake of glucose at tissue level and or increase in pancreatic β-cell function or due to inhibition of intestinal glucose absorption of glucose. The findings of the present study suggest that the methanolic extract of Scoparia dulcis produced significant antihyperglycemic activity in STZ induced diabetic rat which is comparable to Glibenclamide (a standard oral hypoglycaemic agent)." @default.
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- W2376877572 date "2010-01-01" @default.
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- W2376877572 title "Antihyperglycemic activity of flavonoids from methanolic extract of aerial parts of Scoparia dulcis in streptozotocin induced diabetic rats." @default.
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