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- W2376883105 abstract "Objectives To evaluate the right ventricular function in adult patients with atrial septal defect(ASD) after interventional therapy by echocardiography. Methods Sixty adult patients with ASD were in treatment group and30 healthy adults were in control group. Tricuspid annular plane systolic excursion(TAPSE), systolic velocity(S'),end-systolic area(AreaES), end-diastolic area(AreaED) and right ventricular fractional area change(RVFAC) before and after interventional therapy and during the short-term follow-up(6 months after surgery) were measured and compared by echocardiography in both groups. Results There was no statistical difference in age between the two groups[(40.10 ±13.9) years vs.(40.87 ±15.5) years, P =0.849]. Before treatment, AreaES, AreaED, TAPSE and S′ of treatment group were significantly larger than those of control group [(15.28±4.30) cm2vs.(7.27±2.41) cm2, P=0.000;(28.98±6.68) cm2vs.(15.15±3.63) cm2, P0.001;(2.58±0.67)cm vs.(2.25±0.45)cm, P=0.045;(16.5±0.3) cm / s vs.(14.2±2.9)cm / s,P=0.004], while RVFAC was significantly less than that of control group(47.34%±7.26% vs. 52.63%±6.77%,P=0.007). At the first day after interventional therapy, TAPSE and S′ significantly decreased in treatment group[(2.32±0.46) cm vs.(2.58±0.67) cm, P0.01;(12.7±2.6) cm / s vs.(16.5±0.3) cm / s, P0.01], while RVFAC significantly increased 6 months post-operation(50.76% ±3.56% vs. 47.34% ±7.26%, P 0.05). Conclusions Right ventricular function occurs to be limited at the early stage of ASD, but it can gradually return to normal level after inerventional therapy. Evaluation of right ventricular function by echocardiography needs comprehensive indexes." @default.
- W2376883105 created "2016-06-24" @default.
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- W2376883105 date "2014-01-01" @default.
- W2376883105 modified "2023-09-25" @default.
- W2376883105 title "Effct of interventional therapy on right ventricular function in adult patients with atrial septal defect" @default.
- W2376883105 hasPublicationYear "2014" @default.
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