Matches in SemOpenAlex for { <https://semopenalex.org/work/W2376925369> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2376925369 abstract "Objective: To establish a model of acute forebrain ischemia complicated by multiple organ dysfunction syndrome (MODS) , and contribute to the pathogenesis of acute cerebrovascular diseases ( ACVD) complicated by MODS. Methods: Model of cerebral infarction was established by 30minutes of bilateral common carotid artery occlusion. 54 Wistar rats were randomly divided into seven groups: normal control group( n = 6) , sham-operative group( n = 8) and 5 ischemia groups( n =40) including 12h, 24h, 36h, 48,72h five time points. Changes of symptoms and signs including temperature and respiration of each group were recorded. Pathological changes of lung、liver、 intestines and kidney were recorded through optical microscope. Incidences of SIRS and MODS were diagnosed by their criteria. Results: 1. 65% rats of operative groups had abdominal distention in varying degrees. There were significant differences in between operative group and normal control group, between operative group and sham-operative group. 2. Injuries at each time point were observed in lung, liver, intestines, kidney tissues in varying degrees, and lesion of lung was the most serious. There was the consistency between CD 14 mRNA expression and histological changes of ecah organs. 3. Incidences of SIRS and MODS were respectively 100% and 53. 1% after acute forebrain ischemia in rats. Conclusions: An experimental animal model of MODS can be established successfully through acute forebrain ischemia in rats Pathological changes of intestinal mucosa and liver tissues can provide conditions for occurrrence of endotoxin translocation and endotoxemia." @default.
- W2376925369 created "2016-06-24" @default.
- W2376925369 creator A5007341506 @default.
- W2376925369 date "2004-01-01" @default.
- W2376925369 modified "2023-09-27" @default.
- W2376925369 title "Establishment of a model on acute forebrain ischemia complicated by multiple organ dysfunction syndrome (MODS)" @default.
- W2376925369 hasPublicationYear "2004" @default.
- W2376925369 type Work @default.
- W2376925369 sameAs 2376925369 @default.
- W2376925369 citedByCount "1" @default.
- W2376925369 crossrefType "journal-article" @default.
- W2376925369 hasAuthorship W2376925369A5007341506 @default.
- W2376925369 hasConcept C126322002 @default.
- W2376925369 hasConcept C142724271 @default.
- W2376925369 hasConcept C207886595 @default.
- W2376925369 hasConcept C2777714996 @default.
- W2376925369 hasConcept C2778384902 @default.
- W2376925369 hasConcept C2779715522 @default.
- W2376925369 hasConcept C2780091579 @default.
- W2376925369 hasConcept C2780835948 @default.
- W2376925369 hasConcept C2780942790 @default.
- W2376925369 hasConcept C2781156865 @default.
- W2376925369 hasConcept C42219234 @default.
- W2376925369 hasConcept C529278444 @default.
- W2376925369 hasConcept C541997718 @default.
- W2376925369 hasConcept C71924100 @default.
- W2376925369 hasConceptScore W2376925369C126322002 @default.
- W2376925369 hasConceptScore W2376925369C142724271 @default.
- W2376925369 hasConceptScore W2376925369C207886595 @default.
- W2376925369 hasConceptScore W2376925369C2777714996 @default.
- W2376925369 hasConceptScore W2376925369C2778384902 @default.
- W2376925369 hasConceptScore W2376925369C2779715522 @default.
- W2376925369 hasConceptScore W2376925369C2780091579 @default.
- W2376925369 hasConceptScore W2376925369C2780835948 @default.
- W2376925369 hasConceptScore W2376925369C2780942790 @default.
- W2376925369 hasConceptScore W2376925369C2781156865 @default.
- W2376925369 hasConceptScore W2376925369C42219234 @default.
- W2376925369 hasConceptScore W2376925369C529278444 @default.
- W2376925369 hasConceptScore W2376925369C541997718 @default.
- W2376925369 hasConceptScore W2376925369C71924100 @default.
- W2376925369 hasLocation W23769253691 @default.
- W2376925369 hasOpenAccess W2376925369 @default.
- W2376925369 hasPrimaryLocation W23769253691 @default.
- W2376925369 hasRelatedWork W1421918159 @default.
- W2376925369 hasRelatedWork W2056558749 @default.
- W2376925369 hasRelatedWork W2068148268 @default.
- W2376925369 hasRelatedWork W2074822010 @default.
- W2376925369 hasRelatedWork W2094576709 @default.
- W2376925369 hasRelatedWork W2131259544 @default.
- W2376925369 hasRelatedWork W2137894075 @default.
- W2376925369 hasRelatedWork W2355175224 @default.
- W2376925369 hasRelatedWork W2406317983 @default.
- W2376925369 hasRelatedWork W2410398380 @default.
- W2376925369 hasRelatedWork W2460692581 @default.
- W2376925369 hasRelatedWork W2586899710 @default.
- W2376925369 hasRelatedWork W2622638081 @default.
- W2376925369 hasRelatedWork W2899292356 @default.
- W2376925369 hasRelatedWork W2963039613 @default.
- W2376925369 hasRelatedWork W3011932547 @default.
- W2376925369 hasRelatedWork W3029588209 @default.
- W2376925369 hasRelatedWork W3031196484 @default.
- W2376925369 hasRelatedWork W3141962315 @default.
- W2376925369 hasRelatedWork W2076702108 @default.
- W2376925369 isParatext "false" @default.
- W2376925369 isRetracted "false" @default.
- W2376925369 magId "2376925369" @default.
- W2376925369 workType "article" @default.