Matches in SemOpenAlex for { <https://semopenalex.org/work/W2376989102> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2376989102 endingPage "776" @default.
- W2376989102 startingPage "773" @default.
- W2376989102 abstract "Aim The current study was aimed to generate mouse monoclonal antibodies (mAbs) specific for Fc receptor common γ chain (FcRγ), which serves a critical signaling molecule for numerous human immune receptors that play essential roles in human immune responses. Methods Two BALB/c mice were immunized with the synthesized polypeptides containing 19 residues at the carboxyl terminus of human FcR γ chain. The spleen cells from the immunized mice were fused with myeloma Sp2/0 cells. ELISA was used to screen mAbs and the positive clones were selected for further characterization with Western blot and flow cytometry assays. Results After screen, there hybridoma cell lines which secreted mAbs specifically recognized the FcR γ chain were obtained and named as 5B6, 7D3 and 8D4. The 7D3 mAb had the best quality and it could recognize the FcR γ chain in vivo and in vitro with 2.5 μg/mL. Conclusion We have generated the FcRγ-specific mAbs, which may serve as a valuable tool in the functional studies of FcRγ associated immune receptors." @default.
- W2376989102 created "2016-06-24" @default.
- W2376989102 creator A5015260897 @default.
- W2376989102 creator A5043588189 @default.
- W2376989102 creator A5052258913 @default.
- W2376989102 creator A5066160076 @default.
- W2376989102 creator A5070634988 @default.
- W2376989102 date "2011-07-01" @default.
- W2376989102 modified "2023-09-27" @default.
- W2376989102 title "Development and characterization of monoclonal antibody against human FcR γ chain" @default.
- W2376989102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21722532" @default.
- W2376989102 hasPublicationYear "2011" @default.
- W2376989102 type Work @default.
- W2376989102 sameAs 2376989102 @default.
- W2376989102 citedByCount "0" @default.
- W2376989102 crossrefType "journal-article" @default.
- W2376989102 hasAuthorship W2376989102A5015260897 @default.
- W2376989102 hasAuthorship W2376989102A5043588189 @default.
- W2376989102 hasAuthorship W2376989102A5052258913 @default.
- W2376989102 hasAuthorship W2376989102A5066160076 @default.
- W2376989102 hasAuthorship W2376989102A5070634988 @default.
- W2376989102 hasConcept C104317684 @default.
- W2376989102 hasConcept C150903083 @default.
- W2376989102 hasConcept C153911025 @default.
- W2376989102 hasConcept C159654299 @default.
- W2376989102 hasConcept C163864487 @default.
- W2376989102 hasConcept C170493617 @default.
- W2376989102 hasConcept C202751555 @default.
- W2376989102 hasConcept C203014093 @default.
- W2376989102 hasConcept C207001950 @default.
- W2376989102 hasConcept C2776415932 @default.
- W2376989102 hasConcept C2780931953 @default.
- W2376989102 hasConcept C36394416 @default.
- W2376989102 hasConcept C542903549 @default.
- W2376989102 hasConcept C54355233 @default.
- W2376989102 hasConcept C553184892 @default.
- W2376989102 hasConcept C55493867 @default.
- W2376989102 hasConcept C81885089 @default.
- W2376989102 hasConcept C86803240 @default.
- W2376989102 hasConcept C8891405 @default.
- W2376989102 hasConceptScore W2376989102C104317684 @default.
- W2376989102 hasConceptScore W2376989102C150903083 @default.
- W2376989102 hasConceptScore W2376989102C153911025 @default.
- W2376989102 hasConceptScore W2376989102C159654299 @default.
- W2376989102 hasConceptScore W2376989102C163864487 @default.
- W2376989102 hasConceptScore W2376989102C170493617 @default.
- W2376989102 hasConceptScore W2376989102C202751555 @default.
- W2376989102 hasConceptScore W2376989102C203014093 @default.
- W2376989102 hasConceptScore W2376989102C207001950 @default.
- W2376989102 hasConceptScore W2376989102C2776415932 @default.
- W2376989102 hasConceptScore W2376989102C2780931953 @default.
- W2376989102 hasConceptScore W2376989102C36394416 @default.
- W2376989102 hasConceptScore W2376989102C542903549 @default.
- W2376989102 hasConceptScore W2376989102C54355233 @default.
- W2376989102 hasConceptScore W2376989102C553184892 @default.
- W2376989102 hasConceptScore W2376989102C55493867 @default.
- W2376989102 hasConceptScore W2376989102C81885089 @default.
- W2376989102 hasConceptScore W2376989102C86803240 @default.
- W2376989102 hasConceptScore W2376989102C8891405 @default.
- W2376989102 hasIssue "7" @default.
- W2376989102 hasLocation W23769891021 @default.
- W2376989102 hasLocation W23769891022 @default.
- W2376989102 hasOpenAccess W2376989102 @default.
- W2376989102 hasPrimaryLocation W23769891021 @default.
- W2376989102 hasRelatedWork W1981124196 @default.
- W2376989102 hasRelatedWork W1981398264 @default.
- W2376989102 hasRelatedWork W2004142149 @default.
- W2376989102 hasRelatedWork W2013711339 @default.
- W2376989102 hasRelatedWork W2016940124 @default.
- W2376989102 hasRelatedWork W2029804076 @default.
- W2376989102 hasRelatedWork W2031472430 @default.
- W2376989102 hasRelatedWork W2036369606 @default.
- W2376989102 hasRelatedWork W2089467342 @default.
- W2376989102 hasRelatedWork W2185752647 @default.
- W2376989102 hasRelatedWork W2342577506 @default.
- W2376989102 hasRelatedWork W2365167842 @default.
- W2376989102 hasRelatedWork W2388800266 @default.
- W2376989102 hasRelatedWork W2398252525 @default.
- W2376989102 hasRelatedWork W2401679498 @default.
- W2376989102 hasRelatedWork W2410959670 @default.
- W2376989102 hasRelatedWork W2418636073 @default.
- W2376989102 hasRelatedWork W2434834277 @default.
- W2376989102 hasRelatedWork W35533511 @default.
- W2376989102 hasRelatedWork W46445005 @default.
- W2376989102 hasVolume "27" @default.
- W2376989102 isParatext "false" @default.
- W2376989102 isRetracted "false" @default.
- W2376989102 magId "2376989102" @default.
- W2376989102 workType "article" @default.