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- W2376998690 abstract "This trial was conducted to investigate the effects and mechanism of olanzapine(a antagonist of DA and 5-HT) on laying performance of Americal king pigeons.One hundred and twenty couples of 720-day laying pigeons were randomly allocated to four groups(one control and three treatment groups),supplied with 0,0.25,0.75 and 1.25 mg·kg-1 olanzapine,respectively.The experiment period was sixty days.Results indicated that: 1) supplement of 0.75 and 1.25 mg·kg-1 olanzapine in diet increased the laying rate by 20.24%(P0.05) and 23.41%(P0.05),decreased the laying interval by 29.83%(P0.05) and 37.46%(P0.05),respectively;and the serum concentrations of total protein were significantly increased by 7.33%(P0.05) and 11.59%(P0.05) and blood urea nitrogen level significantly decreased by 32.6%(P0.05) and 47.8%(P0.05) in the 0.75 and 1.25 mg·kg-1 olanzapine groups,respectively;2) different levels of olanzapine had no effect on fecundation and incubation rate of the eggs;compared with the control group,0.75 and 1.25 mg·kg-1 olanzapine groups decreased prolactin concentrations by 21.90%(P0.05) and 34.53%(P0.05),increased the follicle-stimulating hormone concentrations by 24.0%(P0.05) and 28.5%(P0.05),and increased the progestin concentrations by 33.7%(P0.05) and 42.0%(P0.05),respectively.It is indicated that olanzapine,as an antagonist of DA and 5-HT,can promote the laying performance of king pigeon by decreasing the prolactin concentration." @default.
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- W2376998690 date "2011-01-01" @default.
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- W2376998690 title "Effect of olanzapine on laying performance of Americal king pigeons and approach to the mechanisms" @default.
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