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- W2377004239 abstract "Objective To investigate the effects of different kinds of chronic liver disease on the clinical features in patients with sporadic Viral Hepatitis E(HE).Methods Two hundred and forty five patients with hepatitis E were selected and reviewed retrospectively.According to the different kinds of underlying liver disease,the patients were divided into following groups: group A(chronic hepatitis B superinfected with HEV,n=67),group B(chronic schistosomiasis superinfected with HEV,n=51),group C(chronic alcoholic liver disease coexisted with HEV,n=49),and group D(the patients infected with HEV alone were randomized as control during the corresponding period,n=78).The peak value of total bilirubin(TBil) and PT-INR,average days stayed in hospital,morbility of fulminant hepatitis and mortality of patients in above all groups was observed.Results The values of above five indexes in group A,B,C and D were(117.43±37.92) μmol/L,1.68±054,(20.85±6.45) d,22.39% and 14.93%;(76.39±23.67) μmol/L,1.03±0.32,(13.47±4.98) d,11.76% and 7.84%;(79.65±24.25) μmol/L,1.08±0.35,(14.91±5.63) d,10.20% and 6.12%;(68.57±21.34) μmol/L,0.99±0.31,(12.56±4.21) d,10.26% and 3.85% respectively.There were significant statistical differences in above five indexes between group A and D(P0.05),but no significant differences between group B and D(P0.05),and between group C and D(P0.05) either.Conclusions More severe hepatic damage would be observed in the patients with chronic hepatitis B after being superinfected with HEV.Morbility of fulminant hepatitis and the mortality of the patients would obviously increase." @default.
- W2377004239 created "2016-06-24" @default.
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- W2377004239 date "2007-01-01" @default.
- W2377004239 modified "2023-09-23" @default.
- W2377004239 title "Effects of chronic liver disease on the clinical features in patients with sporadic viral hepatitis E" @default.
- W2377004239 hasPublicationYear "2007" @default.
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