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- W2377006918 abstract "Objective To study the diagnostic specificity and sensitivity of antinucleosome antibodies(AnuA)in systemic lupus erythematosus(SLE).Methods The serum AnuA and other autoantibodies were detected by immunoblotting method in 90 patients with SLE,40 patients with other rheumatoid diseases and 35 control persons.The relationship among antinucleosome antibodies activity,anti-ds DNA antibody and complements was analyzed.Results The prevalence of AnuA in SLE patients and controls was 72% and 10% respectively,65.2% and 1% for anti-ds DNA,and 22.5% and 0 for anti-Sm antibody.AnuA had a sensitivity of 69.2% and specificity of 96% for SLE diagnosis.The antinucleosome antibody was correlated with SLE diease activity,anti-ds DNA,complement C3 and erythrocyte sedimentation rate.Conclusion The antinucleosome antibody presents a high sensitivity with reasonable specificity to systemic lupus erythematosus and is valuable to diagnose systemic lupus erythematosus." @default.
- W2377006918 created "2016-06-24" @default.
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- W2377006918 date "2007-01-01" @default.
- W2377006918 modified "2023-09-24" @default.
- W2377006918 title "Value of antinucleosome antibody in diagnosis of systemic lupus erythematosus" @default.
- W2377006918 hasPublicationYear "2007" @default.
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