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- W2377026249 abstract "Objective To study the protective effect of milk thistle Yigan tablets on acute hepatic injury induced by carbon tetrachloride.Methods 46 Kunming mice were randomly divided into 4 groups:control,CCl4 control and 2 dosage groups.The two dosage groups were given milk thistle Yigan tablets orally at the doses of 0.13 g/kg and 0.25 g/kg daily.Thirty days later,the two dosage groups and CCl4 control group were given 0.125% CCl4 at the dose of 0.01 ml/g body weight by intraperitoneal injection.The mice were executed respectively after 24 hours.ALT and AST in serum were measured.Pathological changes in livers were observed. Results Compared with CCl4 control group,The levels of ALT and AST were decreased significantly in 0.25 g/kg group (P0.05).The animal number of happening hepatocyte necrosis in group 0.25 g/kg was lowered, the degree of pathobiological changes was lightened,compared with the CCl4 control group,the hepatocyte necrosis evaluation was decreased significantly (P0.05). Conclusion Milk thistle Yigan tablets has protective effect on liver injuries induced by carbon tetrachloride." @default.
- W2377026249 created "2016-06-24" @default.
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- W2377026249 date "2007-01-01" @default.
- W2377026249 modified "2023-09-23" @default.
- W2377026249 title "Study on the protective effect of milk thistle Yigan tablets on acute hepatic injury induced by carbon tetrachloride" @default.
- W2377026249 hasPublicationYear "2007" @default.
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