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- W2377027100 abstract "Objective: To observe the effect of theophylline on the induced sputum cytology of asthma.Method: To study 60 asthma patients,divided them into treatment group and control group randomized.The treatment group took theophylline sustained release tablets 100 mg before breakfast and sleeping,inhaling salbutamol 200 μg,tid.The control group inhaled salbutamol 200 μg,tid.The course of treatment was 8 weeks both of two groups.To examine their induced sputum cytology.Results: Macrophages、 neutrophil、 eosinophils and lymphocytes were main cells in induced sputum of asthma and before the treatment,the number of them are 0.600± 0.137、0.300±0.130、0.093±0.043、0.041±0.022 and 0.630±0.121、0.319±0.099、0.088±0.045、0.037±0.026.After the treatment the macrophages、 neutrophil、 eosinophils and lmphocytes were(2.9±0.52)×106 mL-1 、0.650±0.109、0.280±0.108、0.052±0.037、0.030±0.140 and(2.9±0.58)×106 mL-1、0.641±0.137、0.295±0.069、0.069±0.045、0.032±0.019.The eosinophils ratio decreased compared with before the treatment both of groups and the treatment group was batter than control group(P 0.05).Conclusion: It is suggested that eosinophilic granulocyte is main action cell,in the attack of asthma.Theophylline can reduce of eosinophiles in induced sputum of asthma,it may be one of the mechanisms of the theophylline." @default.
- W2377027100 created "2016-06-24" @default.
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- W2377027100 date "2007-01-01" @default.
- W2377027100 modified "2023-09-23" @default.
- W2377027100 title "Changes of Induced Sputum Cytology with Theophylline in Patients with Asthma" @default.
- W2377027100 hasPublicationYear "2007" @default.
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