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- W2377037498 abstract "Objective To compare matrix metalloproteinase-9(MMP-9)expression in cortex after cerebral ischemia versus thrombolytic therapy with urokinase(UK).Methods Three groups of rats were studied:(1)rats that received UK after ischemia.(2)untreated ischemia controls.(3)rats suffered sham operation.The expres- sion of MMP-9 of the three groups was analysed by immunohistochemistry 24h after ischemia.Results(1)MMP expression apeared after ischemia.(2)UK-treated rats showed significantly higher upregulation of MMP-9 than untreated controls.(3)There was no MMP-9 expression in rats of sham operarion.Conclusion(1)Focal embolic ischemia induce MMP-9 expression.(2)UK treatment significantly upregulates levels of MMP-9 after embolic fo- cal cerebral ischemia." @default.
- W2377037498 created "2016-06-24" @default.
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- W2377037498 date "2007-01-01" @default.
- W2377037498 modified "2023-09-28" @default.
- W2377037498 title "Effects of urokinase on the expression of matrix metalloproteinase-9 during focal cerebral ischemia in rats" @default.
- W2377037498 hasPublicationYear "2007" @default.
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