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- W2377043324 abstract "Objective To study the anti-radical effect of Melatonin( MT) . Method The level of MDA was studied in vitro and in vivo in order to investigated the anti-radical action of MT. Result In vitro, MT(1.0,10 mmol/L) significantly relieved the content of MDA of rats brain homogentes which were induced by hydrogen peroxide or hydroxyl radical. In vivo, MT(1.0,10 mg/kg,ip,12d) could inhibit the increasing content of MDA in mice brain induced by alloxan; MT( 1.0,10 mg/kg,sc,2w)also could relieve the level of MDA in 12-month old mice brain and liver. Conclusion It was suggested that MT could inhibit the oxidative damage of radical by anti- radical effect. It is considered that this effect of MT is likely to be one of its anti-aging mechanisms." @default.
- W2377043324 created "2016-06-24" @default.
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- W2377043324 date "2005-01-01" @default.
- W2377043324 modified "2023-09-27" @default.
- W2377043324 title "Anti-radical action of melatonin" @default.
- W2377043324 hasPublicationYear "2005" @default.
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